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Host cell proteins (HCPs) are a heterogeneous mixture of proteins carried over from the host expression system, and the main impurities in the process of bio-therapeutic manufacturing. The HCPs, either secreted proteins or intracellular proteins released during cell lysis, might influence the enzymatic modification and stability of products, cause failure of a certain purification step, and induce immunogenicity or decreasing activity, etc. FDA and EMA has set the acceptable limits of HCPs, but unknown HCPs at a low level might still leads to an immunogenic effect. To ensure safety and potenc
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Isoelectric point (pI) is one of the important physio-chemical parameters of macromolecules, which represents the pH when the overall net charge equals zero. The net charge of a particular molecule can be affected by the pH of surrounding environment, and the molecule can be more positively or negatively charged through the loss or gain protons. In addition, the pI of a molecule can influence the solubility its solubility at a certain pH and its overall pharmacokinetic behavior. Hence, it's essential to determine the pI of pharmaceutical products. Creative Proteomics will provide you with acc
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Creative Proteomics provides a wide spectrum of nucleotide metabolism services for animal, covering all nucleotide metabolism related metabolites, which advance your science journey or clinical diagnosis for complex diseases.
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Creative Proteomics provides reliable and cost-effective metabolomics services for academia and various industries. Our solutions including untargeted metabolomics service, targeted metabolomics service and lipidomics service.
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Leukotrienes are inflammatory mediators that function in normal host defense and play roles in inflammatory diseases. Creative Proteomics uses liquid chromatography hyphenated to triple quadrupole mass spectrometers for leukotrienes targeted lipidomics.
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The three major types of omega-3 fatty acids involved in human physiology are α-linolenic acid (ALA, C18:3n3), eicosapentaenoic acid (EPA, C20:5n3), and docosahexaenoic acid (DHA, C22:6n3);
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Creative Proteomics provides IL-15 detection services and selects proprietary solutions based on your samples and requirements to assist your experiment.
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Creative Proteomics provides IL-10 detection services and selects proprietary solutions based on your samples and requirements to assist your experiment.
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Metabolomics refers to the systematic identification and quantification of the metabolome of a biological system at a specific point in time. And metabolome means the complete set of small-molecule chemicals found within a biological sample. In metabolomics, metabolites and their concentrations directly reflect underlying biochemical activity and state of cells or tissues. For metabolome profiling, mass spectrometry and NMR are the most commonly used techniques.
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CD ProGPCR is committed to providing universities, research institutions, biotechnology companies and pharmaceutical companies with a wide range of high quality and reliable products and comprehensive service packages of GPCRs to enable advancement of basic science and drug development.
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CD ProGPCR is committed to providing universities, research institutions, biotechnology companies and pharmaceutical companies with a wide range of high quality and reliable products and comprehensive service packages of GPCRs to enable advancement of basic science and drug development.
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CD BioSciences offers advanced techniques for structure-based ligand binding assays, allowing for high-quality and efficient kinase screening & profiling to accelerate kinase research and drug discovery.
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CD BioSciences has a scientific team specializing in kinase biology and drug discovery, providing comprehensive in vitro kinase screening and profiling services for biological research and drug development.
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The organic contaminants ELISA kit customization service provided by Creative Diagnostics provides an effective auxiliary tool for researchers in the process of reducing organic contaminants.
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Creative Diagnostics provides heavy metal ELISA kit customization service that has undergone strict quality control according to customer needs. It can meet customers' testing needs for heavy metals such as lead, cadmium, and copper.
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Denosumab ELISA has been especially developed for the quantitative analysis of free denosumab in serum and plasma samples.
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The Sandwich ELISA kit is used for in vitro quantitative determination of Canakinumab in human serum and plasma samples
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Creative Diagnostics provides Ghrelin antibodies and antigens for intro vitro diagnostics industry and research."
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Creative Diagnostics provides CKBB antibodies and antigens for intro vitro diagnostics industry and research."